Protein Purification
MilliporeSigma™ Calbiochem™ LIM Kinase Inhibitor I, LIMKi 3
The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Pirenzepine Dihydrochloride
An antagonist selective for mAChR subtype M1.
MilliporeSigma™ Calbiochem™ StemSelect™ Compound E
Notch signaling suppressor
MilliporeSigma™ Calbiochem™ Retromer Chaperone, R55
A cell-permeable pharmacological chaperone to increase neuronal retromer levels. Improves Vps35-Vps29-Vps26 retromer complex stability.
MilliporeSigma™ Calbiochem™ Ruthenium Red
A blocker of transmembrane Ca2+ fluxes (IC50 = 7 μM) that attenuates capsaicin-induced cation channel opening.
MilliporeSigma™ Calbiochem™ D-erythro-Sphingosine, N,N-Dimethyl-
A cell-permeable and reversible inhibitor of protein kinase C (PKC; IC50 = 12 μM) and stimulates Src kinase activity.
MilliporeSigma™ Calbiochem™ MMP-12 Inhibitor, MMP408
The MMP-12 Inhibitor, MMP408, also referenced under CAS 1258003-93-8, controls the biological activity of MMP-12. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ HA 1077, Dihydrochloride
A cell-permeable, reversible, and ATP-competitive Ca2+ antagonist with anti-vasospastic properties.
MilliporeSigma™ Calbiochem™ S1P Receptor 2 Agonist, CYM-5520
A potent, selective, allosteric agonist of sphingosine-1-phosphate receptor 2 (S1PR2; EC50 = 480 nM).
MilliporeSigma™ Calbiochem™ Tankyrase1/2 Inhibitor V, WIKI4
A cell-permeable triazole derivative that acts as a reversible TNKS inhibitor (IC50 = 15nM) and selectively inhibits Wnt/β-catenin, but not NF-κB, TGFβ, or retinoic acid, signaling pathway-dependent transcription activ
MilliporeSigma™ Calbiochem™ Diacylglycerol Kinase Inhibitor II
The Diacylglycerol Kinase Inhibitor II, also referenced under CAS 120166-69-0, controls the biological activity of Diacylglycerol KInase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ eIF2-GTP-tRNAiMet ternary complex Inhibitor Negative Control, NCPdCPU
The eIF2-GTP-tRNAiMet ternary complex Inhibitor Negative Control, NCPdCPU controls the biological activity of eIF2-GTP-tRNAiMet ternary complex.
MilliporeSigma™ Calbiochem™ Adenosine A3 Receptor Agonist, 2-Cl-IB-MECA
A highly selective agonist of adenosine A3 receptor (Ki = 330 pM).
MilliporeSigma™ Calbiochem™ Pristimerin
A cell-permeable plant dienone-phenolic triterpenoid, naturally isolated from tripterygium wilfordii.
MilliporeSigma™ Calbiochem™ RNA Polymerase III Inhibitor
RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC50 = 27 and 32 μM for human and S. cerevisiae RNA Pol III, respectively).